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U&E Blood test

At Fusion Healthcare, we offer a private U&E Blood test. Our private U&E blood test evaluates levels of urea and various electrolytes, including sodium, potassium, chloride, and bicarbonate in the bloodstream. A U and E test is commonly used to detect abnormalities of blood chemistry, primarily kidney (renal) function and dehydration. 

Each of these elements plays a vital role in the body: 

  1. Urea: A by-product of protein breakdown, urea is primarily filtered by the kidneys. Elevated urea levels can indicate kidney dysfunction or dehydration, while low levels might suggest malnutrition or liver issues. 
  1. Sodium: Vital for nerve and muscle function, sodium also helps maintain fluid balance. Both high and low sodium levels can cause symptoms like confusion, fatigue, and even seizures. 
  1. Potassium: Essential for heart and muscle activity, potassium is closely regulated in the body. Imbalances can lead to heart irregularities, muscle cramps, or weakness. 
  1. Chloride: This electrolyte helps regulate the body’s acid-base balance and maintain proper fluid levels. Abnormal levels may point to issues with the kidneys or respiratory system. 
  1. Bicarbonate: Bicarbonate helps keep blood pH within the normal range. Deviations can indicate respiratory or kidney-related issues and metabolic imbalances. 

Price: £95.00

Urea

Urea is a waste product of protein breakdown produced in the liver. 3 The kidneys predominantly excrete urea, and it can be used as a surrogate marker of renal function. However, this is fairly non-specific.

Causes of a raised serum urea (uraemia) include:

  • Renal dysfunction: decreased excretion of urea into the urine.
  • Dehydration: urea rises quickly in dehydration, even in the presence of normally functioning kidneys. This is physiologically mediated by anti-diuretic hormone (ADH), released from the posterior pituitary gland in response to intravascular volume depletion. ADH increases urea and water reabsorption in the collecting ducts.
  • Upper gastrointestinal bleeding: blood in the upper GI tract is broken down into proteins, which are transported to the liver via the portal vein and metabolised into urea.

Low serum urea levels are non-pathological, associated with pregnancy and those on a low-protein diet.

Sodium

Sodium is the main determinant of plasma osmolality, and serum levels are closely related to hydration (volume) status. Serum sodium levels are normally regulated by antidiuretic hormone (ADH), amongst other homeostatic mechanisms. Symptoms of both hypernatremia and hyponatremia are primarily neurological. Mild symptoms include fatigue, weakness and confusion, but can progress to severe symptoms such as seizures and coma. The severity of symptoms is related to the severity of sodium derangement and the pace of the change in serum sodium concentration (rapid changes lead to severe symptoms)
  • Hypernatremia is defined as a serum sodium level >146mmol/L. It is most commonly caused by dehydration (e.g. unreplaced skin or GI losses of hypotonic fluid).
  • Hyponatraemia is defined as a serum sodium level <135mmol/L. It is often caused by a failure to excrete water normally (e.g. SIADH).

Sodium

Sodium is the main determinant of plasma osmolality, and serum levels are closely related to hydration (volume) status. Serum sodium levels are normally regulated by antidiuretic hormone (ADH), amongst other homeostatic mechanisms. Symptoms of both hypernatremia and hyponatremia are primarily neurological. Mild symptoms include fatigue, weakness and confusion, but can progress to severe symptoms such as seizures and coma. The severity of symptoms is related to the severity of sodium derangement and the pace of the change in serum sodium concentration (rapid changes lead to severe symptoms)
  • Hypernatremia is defined as a serum sodium level >146mmol/L. It is most commonly caused by dehydration (e.g. unreplaced skin or GI losses of hypotonic fluid).
  • Hyponatraemia is defined as a serum sodium level <135mmol/L. It is often caused by a failure to excrete water normally (e.g. SIADH).

Potassium

Derangements in potassium levels are common in hospital inpatients. Under physiological conditions, potassium is stored almost entirely intracellularly and is excreted by the kidneys. Derangements in potassium levels cause myocardial instability, leading to risks of potentially fatal arrhythmias.

What are U&E blood tests used for?

U&E blood tests are often ordered to: 

  • Assess kidney function: Since the kidneys filter blood and remove waste, urea and electrolyte levels can indicate how well they’re functioning. 
  • Monitor chronic conditions: Many chronic diseases like diabetes, high blood pressure, and heart disease affect electrolyte levels and kidney function. Regular U&E tests can help monitor and manage these conditions. 
  • Evaluate symptoms: Symptoms like fatigue, confusion, swelling, and muscle weakness may stem from electrolyte imbalances or kidney problems. 
  • Prep for surgery or certain treatments: U&E tests are commonly ordered before surgery or starting medications that may affect kidney function. 

Factors that may affect test results

Certain lifestyle factors, medications, and health conditions can influence U&E results. Common factors include: 

  • Dehydration: Low fluid intake or high fluid loss can lead to elevated urea and altered electrolyte levels. 
  • Medications: Diuretics, certain blood pressure meds, and treatments like chemotherapy can impact kidney function and electrolyte balance. 
  • Diet and lifestyle: High protein intake can increase urea, while diets lacking in essential nutrients may affect other values. 

Preparing for a U&E blood test

In most cases, no special preparation is needed before a U&E blood test. However, you should: 

  • Stay Hydrated: Avoid dehydration by drinking enough water before the test. 
  • Avoid Certain Medications: Your GP may advise you to avoid specific medications before the test, as they can affect results. 
  • Discuss Supplements: Let your GP know if you take any supplements, as some can impact electrolyte levels. 

When to have a U&E blood test

If you’re experiencing symptoms like fatigue, confusion, unusual thirst, or muscle cramps, it might be helpful to have a private U&E blood test with Fusion Healthcare. Additionally, if you have a chronic condition, regular U&E tests can help you and your healthcare provider monitor your kidney health and make necessary adjustments to your treatment plan. The private U&E performed at Fusion Healthcare will provide you with results within 24-48 hours. 

FAQ: Blood Test Service

How do I prepare for a blood test?

Preparation for a blood test may vary depending on the type of test. Generally, you may need to fast for 8-12 hours before the test, avoid certain medications, and stay hydrated. Our team will provide specific instructions based on your test.

How long does it take to get the results?

The turnaround time for blood test results depends on the specific test. Most standard tests are completed within 24-48 hours, while specialized tests may take a bit longer. We will inform you of the expected time frame when you have your test done.

Are the blood tests covered by insurance?

Coverage for blood tests varies depending on your insurance plan. We recommend checking with your insurance provider to understand what tests are covered. Our team can also assist you with any insurance-related queries.

How can I book a blood test appointment?

Booking a blood test appointment at Fusion Healthcare is easy. You can schedule your appointment online through our website, call us at 01582 249 449, or email us at info@fusion-radiology.com. We offer flexible appointment times to accommodate your schedule.

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